Figure4.

Effects of resveratrol manifested by ameliorated glucose tolerance and enlarged adipocytes. (A) Experimental design flow chart. (B–E) Plasma glucose levels are shown inmg/dl for rat models (n = 6–9 for each group) after glucose administration for glucose tolerance test (GTT) ((Band D), panels on the left) or after insulin administration for insulin tolerance test (ITT) ((Cand E), panels on the left). Areas under GTT or ITT glucose curves were calculated per 120 minutes, for EMs and for controls, respectively ((B–E), panels on the right). Plasma glucose levels were measured for aliquots of GTT or ITT samples from 0, 30-, 60-, 90- or 120-min time points. (F) Histology of gonadal adipose tissue from rat models. Scale bar 20 μm. (G) Statistical image of adipocyte size in gonadal adipose tissue. Data are presented as mean ± SEM, *P < 0.05; **P < 0.01 EMs vs control, ^##P< 0.01 Res-high vs control (ANOVA).

Abbreviations: Res-med, dose = 15 mg/Kg/d; Res-high, dose = 45 mg/Kg/d; ns, no significance.