Table 1.

I-STAR Study Timeline and Milestones

MILESTONES	Year 1				Year 2				Year 3				Year 4				Year 5
	1	2	3	4	1	2	3	4	1	2	3	4	1	2	3	4	1	2	3	4
Start-up	x
Training personnel/IRB approvals/finalize measures	x
Formative Phase		x	x	x	x
Finalize SBIRT-CTS and mSBIRT training and supervision manuals and piloting		x	x	x
Finalize data collection/management and Manual of Procedures				x
Trainer of trainers/harmonize trainings					x
Effectiveness-lmplementation type 2 RCT (Aim 1 & 2)						x	x	x	x	x	x	x	x
RCT Implementation Phase						x	x	x	x
Training of CHWs and PCPs						x	x
Service, consultation, monitoring and feedback								x	x
RCT Sustainability Phase										x	x	x	x
Competency										x	x	x	x
Cost-Effectiveness Data Analysis										x	x	x	x	x	x
Scale-up of Most Effective Arm - cross over																x	x	x	x
Mixed-Methods Process Evaluation (Aim 3)							x	x	x	x	x	x	x	x	x	x	x	x	x
Conduct Focus Groups and Interviews							x	x	x	x	x	x	x	x	x	x	x	x	x
Ongoing Quan/Qual Data							x	x	x	x	x	x	x	x	x	x	x	x	x
Analysis
Finalize Tool-kit Development																		x	x	x
Policy Workshop																				x

Note: IRB – Institutional Review Board; SBIRT-CTS – Screening, Brief Intervention and Referral to Treatment Conventional Training and Supervision; mSBIRT – mobile health Screening, Brief Intervention and Referral to Treatment; CHW – Community Health Worker; PCP – Primary Care Provider