Table 3:

Effects of replacing lighter intensities with equal periods of walking at a moderate intensity on risk for KR over five years in adults with advanced structural knee OA (Kellgren and Lawrence grade ≥3 in one or both knees) (N=516).

Walking intensity	Unadjusted HR [95%CI]	Adjusted HR [95%CI]†
Replacing 10 mins/day of very-light walking‡ with 10 mins/day of
Moderate walking‡‡	0.62 [0.42, 0.92]*	0.65 [0.45, 0.94]*
Replacing 10 mins/day of light walking‡‡‡ with 10 mins/day of walking at
Moderate walking‡‡	0.57 [0.35, 0.92]*	0.63 [0.40, 1.00]*

HR=hazard ratio CI=confidence interval

^†Adjusted for age, BMI, sex, education, race, index knee pain defined using most painful knee on VAS scale, comorbidities, and previous knee injuries/surgeries

^‡Very-light walking is defined as time spent in 1–49 steps/min

^‡‡Moderate walking is defined as time spent in 50–100 steps/min

^*Denotes statistical significance, i.e., p-value<0.05 and 95%CI does not cross 1

^‡‡‡Light walking is defined as time spent in >100 steps/min