Table 2.
Intraday and Interday precision and accuracy of 3-oxopentanoic acid in human plasma (intraday (n=6), interday (n=18))
| Quality Control Standards, Nominal Concentrations (μg/mL) | ||||||
|---|---|---|---|---|---|---|
|
|
||||||
| Parameter | Run | n | 0.156 (LLOQ) | 0.450 (LQC) | 4.00 (MQC) | 8.00 (HQC) |
|
| ||||||
| Mean (μg/mL) | 1 | 6 | 0.17 | 0.45 | 3.9 | 7.8 |
| Accuracy (%RE)a | 1 | 6 | 6.2 | −0.6 | −2.0 | −2.9 |
| Precision (%RSD)b | 1 | 6 | 7.2 | 3.8 | 3.2 | 4.0 |
| Mean (μg/mL) | 2 | 6 | 0.15 | 0.43 | 4.1 | 8.4 |
| Accuracy (%RE)a | 2 | 6 | −7.1 | −5.5 | 2.6 | 5.0 |
| Precision (%RSD)b | 2 | 6 | 7.2 | 3.4 | 4.0 | 4.6 |
| Mean (μg/mL) | 3 | 6 | 0.15 | 0.45 | 4.4 | 9.0 |
| Accuracy (%RE)a | 3 | 6 | −1.2 | 0.8 | 9.7 | 12 |
| Precision (%RSD)b | 3 | 6 | 6.5 | 3.0 | 2.3 | 1.8 |
| Mean (μg/mL) | 1,2,3 | 18 | 0.15 | 0.44 | 4.1 | 8.4 |
| Accuracy (%RE)a | 1,2,3 | 18 | −0.7 | −1.8 | 3.4 | 4.7 |
| Precision (%RSD)b | 1,2,3 | 18 | 8.6 | 4.3 | 5.7 | 6.9 |
a
= Percent Relative Error
b
= Percent Relative Standard Deviation