TABLE 1.

LASSO regression result of Parkinson’s disease gene family in TCGA-LUAD dataset.

Gene symbol	Full name	Function
PARK3(SFXN5)	sideroflexin-5	mitochondrial amino-acid transporter
PARK14(PLA2G6)	calcium-independent phospholipase A2	involved in cellular membrane homeostasis, mitochondrial integrity and signal transduction
PARK16(RAB29)	ras-related protein Rab-7L1	Involved in vesicle trafficking
PARK16(SLC41A1)	solute carrier family 41 member 1	a predominant Mg2+ efflux system at the plasma membrane
PARK18(EIF4G1)	eukaryotic translation initiation factor 4 gamma 1	component of the protein complex eIF4F
PARK21(DNAJC13)	dnaJ homolog subfamily C member 13	involved in membrane trafficking through early endosomes
PARK22(CHCHD2)	coiled-coil-helix-coiled-coil-helix domain-containing protein 2	transcription factor