TABLE 3.
Characteristic skin transport parameters from various ACE formulations.
| Formulation code | Cumulative drug permeated in 24 h (Q24) (µg) | Permeability coefficient (P) (cm−2.h−1) | Steady state permeation flux (jss) (µg/cm2 h) | ER |
|---|---|---|---|---|
| CA-NLC | 3250.46 ± 18.73 | 2.10E-02 | 118.41 | 1.59 |
| SA-NLC | 2840.14 ± 17.92 | 1.75E-02 | 98.92 | 1.33 |
| GMS-NLC | 2250.83 ± 15.31 | 1.86E-02 | 104.90 | 1.41 |
| CA-NLC-gel | 2600.52 ± 19.28 | 1.89E-02 | 106.43 | 1.43 |
| SA-NLC-gel | 2400.17 ± 17.19 | 1.58E-02 | 88.98 | 1.2 |
| GMS-NLC-gel | 2750.15 ± 24.28 | 9.89E-03 | 55.76 | 0.75 |
| Mkt-gel | 1240.59 ± 12.28 | 1.31E-02 | 74.14 | 1 |