Table 3.
Results of univariate and multivariable cox regression comparing the hazards of death of de novo metastatic patients with lung metastasis vs. those without lung metastasis.
| Univariate Analysis | HR | 95% CI | P -value |
|---|---|---|---|
| Lung metastasis vs. no lung metastasis | 1.18 | [1.17–1.19] | <0.001 |
| Multivariable Analysis | |||
| Lung metastasis vs. no lung metastasis | 1.22 | [1.21–1.23] | <0.001 |
| Male vs female sex | 1.12 | [0.89–1.11] | <0.001 |
| Year of diagnosis (per each year increase) | 0.98 | [0.98–0.98] | <0.001 |
| Age (per each year increase) | 1.02 | [1.02–1.02] | <0.001 |
| T-Stage | |||
| T0 vs. T1 | 1.13 | [1.10–1.17] | <0.001 |
| T2 vs. T1 | 1.19 | [1.17–1.21] | <0.001 |
| T3 vs. T1 | 1.10 | [1.09–1.12] | <0.001 |
| T4 vs. T1 | 1.29 | [1.28–1.31] | <0.001 |
| TX vs. T1 | 1.48 | [1.45–1.50] | <0.001 |
| N-Stage | |||
| N+ vs. N0 | 1.17 | [1.16–1.19] | <0.001 |
| NX vs. N0 | 1.17 | [1.16–1.18] | <0.001 |
| Race | |||
| American Indian/Alaska Native vs. White | 1.03 | [0.98–1.08] | 0.193 |
| Asian/Pacific Islander vs. White | 0.86 | [0.85–0.88] | <0.001 |
| Black vs. White | 1.07 | [1.06–1.08] | <0.001 |
| Unknown vs. White | 0.50 | [0.44–0.55] | <0.001 |
| Co-existing bone/brain/liver metastasis vs. no bone/brain/liver metastasis | 1.25 | [1.24–1.26] | <0.001 |
HR, hazard ratio; CI, confidence interval.