Table 1.
Baseline characteristics of patients with HFmrEF and HFpEF.
| Characteristics | Chioncel et al. (3) | Wang et al. (5) | Tsuji et al. (14) | Lund et al. (13) | Moliner et al. (15) | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| HFmrEF | HFpEF | HFmrEF | HFpEF | HFmrEF | HFpEF | HFmrEF | HFpEF | HFmrEF | HFpEF | |
| n = 2,212 | n = 1,462 | n = 6,825 | n = 13,497 | n = 596 | n = 2,154 | n = 1,322 | n = 1,953 | n = 134 | n = 135 | |
| Age (years) | 64.2 ± 14.2 | 68.6 ± 13.7 | 67.7 ± 13.3 | 71.3 ± 12.5 | 69.0 ± 11.6 | 71.7 ± 10.9 | 65 ± 11 | 67 ± 11 | 67 ± 12 | 69.6 ± 14.4 |
| Female gender (%) | 31.5 | 47.9 | 35.2 | 50.2 | 28.2 | 39.2 | 29.9 | 45.5 | 32.1 | 60.7 |
| BMI (kg/m2) | 28.6 ± 5.4 | 28.4 ± 5.4 | 24.0 ± 4.0 | 24.2 ± 4.2 | 22.8 ± 5.3 | 23.2 ± 4.7 | 27.8 (25.0–31.2) | 28.6 (25.4–32.6) | 28.6 ± 5.4 | 28.6 ± 5.4 |
| SBP (mmHg) | 126.5 ± 21.1 | 130.98 ± 21.4 | 131.3 ± 22.4 | 134.9 ± 22.9 | 124.7 ± 19.3 | 127.9 ± 19.2 | 130 (120–145) | 140 (124–150) | 132.4 ± 20.6 | 135.4 ± 25.7 |
| NYHA class III–IV, n (%) | 18.4 | 20.3 | 36.2 | 41.6 | 11.7 | 10.6 | 42.3 | 38.9 | 28.4 | 34.8 |
| IHD (%) | 41.8 | 23.7 | 60.8 | 57.1 | 52.9 | 44.1 | 66.9 | 50.4 | 54.5 | 13.3 |
| DCM (%) | 27.6 | 11.6 | 10.6 | 2.9 | 20.3 | 6.4 | 6.7 | 1.5 | ||
| Hypertension (%) | 9.6 | 18.1 | 59.4 | 64.5 | 89.8 | 91.2 | 56.2 | 68.7 | 66.4 | 74.8 |
| AF (%) | 22.3 | 32.2 | 33.0 | 40.9 | 43.5 | 51.8 | 25.6 | 31.3 | 22.4 | 38.5 |
| DM (%) | 30.5 | 29.3 | 30.7 | 28.5 | 36.1 | 33.8 | 28.6 | 28.1 | 29.9 | 37.8 |
| MI | 39.4 | 22.4 | 41.1 | 26.9 | 57.6 | 37.0 | ||||
| COPD (%) | 11.6 | 14.0 | 7.4 | 9.6 | ||||||
| Prior stroke/TIA (%) | 8.3 | 9.8 | 14.6 | 17.5 | 22.1 | 21.9 | 9.3 | 8.4 | ||
| Chronic kidney disease (%) | 16.5 | 19.9 | 11.9 | 11.0 | ||||||
| LBBB (%) | 15.4 | 8.7 | 5.0 | 2.3 | ||||||
| Anemia | 28.5 | 31.7 | ||||||||
AF, atrial fibrillation/flutter; BMI, body mass index; COPD, chronic pulmonary obstructive disease; DCM, dilated cardiomyopathy; DM, diabetes mellitus; IHD, ischemic heart disease; LBBB, left bundle branch block; MI, myocardial infarction; NYHA, New York Heart Association; SBP, systolic blood pressure; TIA, transient ischemic attack.