FIGURE 1.

Schematic diagram showing the structure and specific domains of three subfamilies of chromodomain helicase DNA-binding (CHD) proteins. This figure briefly demonstrates the basic structure and domains of CHD protein family. As is reviewed in section “Introduction of CHD Superfamily” of this article, CHD proteins are mainly divided in three subfamilies by their specific domains, subfamily I with basic chromodomian and sucrose non-fermentable2 (SNF2)-like ATP-dependent helicase domain, subfamily II with additional PHD zinc finger domain, and subfamily III with additional SANT domain and BRK domain. The simple geometric patterns represent the protein domains, whose size or location are not strictly to scale, just for brief demonstration.