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. 2021 Aug 10;62:100104. doi: 10.1016/j.jlr.2021.100104

Figure 3.

Figure 3

Classification of disease groups by lipid markers. A: Classification of steatotic and nonsteatotic patients reported as an area under the curve (AUC) for precision recall (PR) and receiver operator characteristics (ROC). Classification based on all lipids (upper panel) and only by the ratio of SM 43:1;2 and SM 43:3;2 normalized to SM 38:2;2 (lower panel). B: Changes in the abundance of SM species in steatotic (red background) and nonsteatotic (blue background) components. SM 38:2;2 belongs to none of the two components (gray background). Lines indicate disease progression: NC (blue), HO (green), NAFL (yellow), and NASH (red) patient groups. Axes indicate relative abundances of SM species; data points per species sum up to 100%. C: Medians of the ratios of the abundance of SM 43:1;2 to SM 38:2;2 and SM41:3;2 to SM 38:2;2 for the patient groups, including subgroups of NAFL (D) Classifications of all patient groups against each other using the two SM ratios.