Table 2.

PNPLA3 and MBOAT7 mutation-dependent changes of lipidome in NASH and NC groups

Lipida	Mutation	Group	Mutation Status	Abundance Ratio
CE 22:2	PNPLA3 rs738409	NASH	Heterozygote/No mutation	4.0b
TG 56:7	PNPLA3 rs738409	NASH	Heterozygote/No mutation	6.8c
TG 56:7	PNPLA3 rs738409	NASH	Homozygote/No mutation	15.1c
TG 56:7	PNPLA3 rs738409	NASH	Homozygote/Heterozygote	2.2b
PI 36:1	MBOAT7 rs641738	NC	Heterozygote/No mutation	2.2b
PI 36:1	MBOAT7 rs641738	NC	Homozygote/No mutation	4.5d

^aSignificantly changed lipid in the two compared groups.

^bSignificance P < 0.05.

^cSignificance P < 0.005.

^dSignificance P < 0.01.