Table 3.
Factors Associated with Secondary and Primary Prevention Aspirin Use Stratified by Number of Traditional ASCVD Risk Factors, Behavioral Risk Factor Surveillance System (2019).
| Characteristics | No CVD Primary Prevention |
CVD Secondary Prevention |
||||
|---|---|---|---|---|---|---|
| Absence of self-reported ASCVD risk factors |
Presence of ≥3 self-reported ASCVD risk factors |
|||||
| aOR [95% CI] | p-value* | aOR [95% CI] | p-value* | aOR [95% CI] | p-value† | |
| Sex | ||||||
| Female | Ref | Ref | Ref | |||
| Male | 1.60 [1.12–2.27] | 0.009 | 1.12 [0.91–1.37] | 0.28 | 1.56 [1.23–1.99] | <0.001 |
| Age, years | ||||||
| 40–69 | Ref | Ref | Ref | |||
| ≥70 | 3.22 [2.27–4.55] | <0.001 | 1.88 [1.53–2.30] | <0.001 | 1.17 [0.93–1.48] | 0.19 |
| Race/ethnicity | ||||||
| Non-Hispanic White | Ref | Ref | Ref | |||
| Non-Hispanic Black | 0.53 [0.24–1.16] | 0.11 | 1.44 [1.03–2.02] | 0.035 | 1.22 [0.77–1.94] | 0.40 |
| Hispanic | 0.70 [0.32–1.56] | 0.38 | 0.64 [0.44–0.92] | 0.017 | 0.96 [0.60–1.53] | 0.86 |
| Other | 0.49 [0.20–1.24] | 0.13 | 0.91 [0.56–1.48] | 0.70 | 0.93 [0.58–1.48] | 0.76 |
| Income, poverty line | ||||||
| Below | Ref | Ref | Ref | |||
| Within 100–200% | 1.44 [0.50–4.16] | 0.50 | 1.13 [0.73–1.73] | 0.58 | 0.88 [0.57–1.36] | 0.56 |
| >200% | 1.13 [0.47–2.71] | 0.78 | 0.93 [0.63–1.36] | 0.69 | 1.11 [0.73–1.69] | 0.63 |
| Healthcare coverage | ||||||
| No | Ref | Ref | Ref | |||
| Yes | 2.28 [1.17–4.44] | 0.015 | 1.14 [0.73–1.77] | 0.58 | 1.34 [0.82–2.19] | 0.24 |
| Education | ||||||
| Less than high school | Ref | Ref | Ref | |||
| High school/Some college | 0.92 [0.39–2.18] | 0.85 | 0.83 [0.58–1.20] | 0.33 | 1.25 [0.86–1.82] | 0.24 |
| College graduate | 0.85 [0.34–2.13] | 0.73 | 0.88 [0.61–1.29] | 0.52 | 1.24 [0.82–1.89] | 0.31 |
| General health status | ||||||
| Good/excellent | Ref | Ref | Ref | |||
| Poor/fair | 1.51 [0.84–2.70] | 0.17 | 1.09 [0.88–1.36] | 0.42 | 1.08 [0.83–1.40] | 0.56 |
| ASCVD Risk Factors | ||||||
| 0 | – | – | Ref | |||
| 1 | 1.19 [0.64–2.19] | 0.58 | ||||
| 2 | 2.03 [1.13–3.65] | 0.017 | ||||
| ≥3 | 2.33 [1.33–4.10] | 0.003 | ||||
ASCVD Risk Factors: hypertension, diabetes, high cholesterol, overweight/obesity, and current combustible cigarette smoking.
ASCVD: atherosclerotic cardiovascular disease.
aOR: adjusted odds ratio.
CI: confidence interval.
CVD: cardiovascular disease.
⁎
Adjusted for age, sex, race, income, healthcare coverage, education, and self-reported health status.
†
Additionally adjusted for the number of ASCVD risk factors.