Table 4.
Logistic analysis of factors related to the progression of patients with COVID-19
| Variables | Univariate | Multivariate | ||
| OR (95% CI) | P value | OR (95% CI) | P value | |
| Age (＞65 years) | 3.301 (2.318 to 4.701) | <0.001 | ||
| Gender (male） | 2.160 (1.528 to 3.054) | <0.001 | ||
| Hypertension | 2.085 (1.419 to 3.062) | <0.001 | ||
| Cardiovascular disease | 2.027 (1.423 to 2.887) | <0.001 | ||
| Chronic respiratory disease | 1.648 (1.036 to 2.621) | 0.035 | ||
| Oxygenation index | 0.985 (0.983 to 0.988) | <0.001 | ||
| Arterial oxygen partial pressure | 0.958 (0.949 to 0.967) | <0.001 | 0.958 (0.943 to 0.974) | <0.001 |
| C reactive protein | 1.031 (1.025 to 1.038) | 0.001 | 1.015 (1.001 to 1.029) | 0.034 |
| Serum amyloid A | 1.002 (1.000 to 1.005) | 0.108 | ||
| Erythrocyte sedimentation rate | 1.057 (1.035 to 1.080) | <0.001 | ||
| NLR | 1.282 (1.219 to 1.348) | <0.001 | 1.105 (1.003 to 1.219) | 0.044 |
| PLR | 1.005 (1.004 to 1.006) | <0.001 | ||
| SII | 1.001 (1.001 to 1.001) | <0.001 | ||
| Albumin | 0.841 (0.809 to 0.874) | <0.001 | ||
| Lymphocytes count | 0.922 (0.765 to 0.972) | 0.043 | ||
| D-dimer | 1.757 (1.403 to 2.201) | <0.001 | 1.286 (1.022 to 1.618) | 0.032 |
| Prothrombin time | 1.138 (1.023 to 1.265) | 0.017 | ||
Univariate and multivariate analyses were carried out using a logistic regression model. P<0.05 was considered statistically significant.
NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; SII, systematic immune-inflammatory index.