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. 2021 Sep 20;12:672846. doi: 10.3389/fimmu.2021.672846

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Copyright © 2021 Zhao, Zhao, Chen, Zhang, Li, Liu, Lv, Wang and Ai

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The comparison of metabolism using the 18F-FDG PET scans of patients with FBDS and those without FBDS and healthy controls by SPM analysis. The T-maps show the hypo-metabolism (cold) and hyper-metabolism (hot colors). The SPM T-maps were projected onto surface, rendering and axial views of the MNI 152 template. The number in each transaxial brain image indicates the distance (mm) from the anterior commissure-posterior commissure plane. (A) Compared to patients without FBDS, the glucose metabolism increased in the bilateral putamen and left cerebellum of patients with FBDS. P = 0.001 without correction. R, right; L, left.(B) Compared to healthy controls, the glucose metabolism increased in the bilateral putamen, and decreased in the right frontal lobe of patients with FBDS. P = 0.001 was corrected. R, right; L, left.