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. 2021 Sep 20;12:739768. doi: 10.3389/fimmu.2021.739768

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Copyright © 2021 Sun, Xie, Zhang, Wang, Huang and Xia

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Validation and application of the m⁶A score in the clinical evaluation. (A) The AUC values of the 1-year, 3-year, and 5-year ROC curves of m⁶A score in all samples. (B) The AUC values of the 1-year, 3-year, and 5-year ROC curves of m⁶A score in the TCGA-PAAD cohort. (C) The comparation of 1-year ROC curve with other clinical characteristics in the TCGA-PAAD cohort. (D) Univariate COX regression analysis showed that age, grade, and m⁶A score were considered statistically significant. (E) Multivariate Cox regression analysis showed age and m⁶A score were independent prognostic predictors. (F) The nomogram to predict the probability of 1-year, 3-year, and 5-year survival rate. (G) The AUC values of the 1-year, 3-year, and 5-year ROC curves of the nomogram. ***P < 0.001; **P < 0.01; *P < 0.05.