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IL-10 neutralization worsens psoriatic symptoms and epidermal thickness in the IMQ-induced psoriasis mouse model. (A) At day 10, scores for skin scaling, thickness, redness and PASI in various groups following IMQ treatment. (B) Measured average epidermal thickness in psoriasis-like skin at days 5 and 10, and thickness ratios compared to isotype antibody controls at days 5 and 10. Data are shown as means ± SEMs. *P < 0.05, **P < 0.01, and ***P < 0.001.
