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. 2021 Sep 20;9:718377. doi: 10.3389/fbioe.2021.718377

FIGURE 6.

FIGURE 6

(A) Dextran-allyl isocyanate-ethylamine (Dex-AE)/polyethylene glycol diacrylate (PEGDA) hydrogel promotes neovascularization: Precise structure manipulation results in rapid, efficient, and functional neovascularization (Sun et al., 2011). Images were adapted with permission from Sun et al. (2011). Copyright 2011, National Academy of Sciences. (B) Chemical structure of self-crosslinkable dextran-isocyanatoethyl methacrylate-ethylamine (DexIEME) (Sun, 2017). Images were adapted with permission from Sun (2017). Copyright 2017, John Wiley and Sons. (C) Chemokine sequestration by the starPEG-heparin hydrogel networks (depicted in A) through strong electrostatic interactions of heparin derivatives and chemokines (depicted in B) results in a reduced immune cell invasion, which in turn, lowers the concentrations of inflammatory chemokines and ultimately allows the inflammation to subside (Lohmann et al., 2017). Images were adapted with permission from Lohmann et al. (2017). Copyright 2017, The American Association for the Advancement of Science.