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. 2021 Sep 20;9:620531. doi: 10.3389/fpubh.2021.620531

Table 3.

Adjusted VE of PPV23 vaccination against pneumococcal diseases among people aged 60 years or older.

Multivariable adjustments Adjusted VE,% (95%CI) P
Overall
   Model 1 24 (3, 41) 0.030
   Model 2 25 (4, 42) 0.025
   Model 3 25 (3, 42) 0.030
Stratified by gender
Male
   Model 1 17 (−11, 37) 0.215
   Model 2 17 (−11, 38) 0.203
   Model 3 17 (−11, 38) 0.213
Female
   Model 1 47 (9, 70) 0.023
   Model 2 50 (13, 72) 0.015
   Model 3 49 (11, 71) 0.019

Model 1: Adjusted for age, medical history (respiratory related diseases, chronic underlying diseases and immune system diseases) and smoking status.

Model 2: Adjusted for age, medical history (respiratory related diseases, chronic underlying diseases and immune system diseases), smoking status and co-infection with other pathogens.

Model 3: Adjusted for age, medical history (respiratory related diseases, chronic underlying diseases and immune system diseases), smoking status, co-infection with other pathogens, antibiotics using before sampling and influenza vaccination within previous year.