FIGURE 4.

(A–F) Association between change in psychosocial predictors over time and trajectory group. Results from generalized estimating equation models. Panel A displays a significant difference between trajectory groups for change in eating self‐efficacy (measured with the Weight Exercise Lifestyle questionnaire) over time. For every 1 month increase in the study, among weight regainers, eating self‐efficacy decreased by 0.39 units (95% CI: 0.07, 0.70), while weight loss maintainers increased by 0.42 units (95% CI: −0.002, 0.84), on average (false discovery rate [FDR]‐adjusted p < 0.01). Panel B displays a significant difference between trajectory groups for change in cognitive restraint (measured with the Three‐Factor Eating Inventory [TFEI]) over time. For every 1 month increase in the study, among weight regainers, cognitive restraint increased by 0.14 units (95% CI: 0.09, 0.18), while weight loss maintainers increased by 0.29 units (95% CI: 0.24, 0.34) on average (FDR‐adjusted p < 0.01). Panel C displays a significant difference between trajectory groups for change in disinhibition (measured with TFEI) over time. For every 1 month increase in the study, among weight regainers, disinhibition decreased by 0.02 units (95% CI: −0.05, 0.01), while weight loss maintainers decreased by 0.08 units (95% CI: −0.12, −0.03) on average (FDR‐adjusted p = 0.047). Panel D displays a significant difference between trajectory groups for change in self‐reported weight management behaviors (measured using the total score from the Eating Behavior Inventory Revised) over time. For every 1 month increase in the study, among weight regainers, engagement in weight management behaviors increased by 0.02 units (95% CI: 0.02, 0.03), while weight loss maintainers increased by 0.06 units (95% CI: 0.05, 0.06), on average (FDR‐adjusted p < 0.01). Panel E displays a significant difference between trajectory groups for change in autonomous motivation to engage in weight loss treatment (measured with the Treatment Self‐Regulation Questionnaire) over time. For every 1 month increase in the study, among weight regainers, autonomous motivation for weight loss treatment decreased by 0.04 units (95% CI: 0.02, 0.04), while weight loss maintainers decreased by 0.003 units (95% CI: −0.01, 0.009) on average (FDR‐adjusted p < 0.01). Panel F displays a significant difference between trajectory groups for change in depressive symptoms (measured with the Center for Epidemiologic Studies Depression Scale) over time. For every 1 month increase in the study, among weight regainers, depressive symptoms increased by 0.15 units (95% CI: 0.09, 0.22), while weight loss maintainers decreased by 0.003 units (95% CI: −0.09, 0.08) on average (FDR‐adjusted p = 0.01). At 0, 6, 12, 18, and 24 months, respectively, maintainers (n = 5, n = 6, n = 6, n = 6, n = 2, respectively), and regainers (n = 2, n = 7, n = 13, n = 9, n = 5, respectively) had depression scores ≥16