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. 2021 Sep 28;6(3):146–152. doi: 10.1016/j.ncrna.2021.09.002

Fig. 5.

Fig. 5

Schematic diagram of the implicated signaling pathway relating to the anti-inflammatory effects of miR-499a by inhibits PTEN expression through targeting its 3ʹ-UTR on ischemic stroke (IS). The upregulated miR-499a induces production of pro-inflammatory cytokines including IL-6 and TNF-α.