Table 4.
Distribution of PD1.3 and IL28B rs12979860 genotypes in AIH patients and healthy controls.
| AIH patients (n = 200) | Controls (n = 100) | Model | P-value | |
|---|---|---|---|---|
| PD1.3 (rs11568821) | ||||
| Genotype | ||||
| GG | 164 (82%) | 72 (72%) | Codominant | 0.132 |
| GA | 34 (17%) | 26 (26%) | ||
| AA | 2 (1%) | 2 (2%) | ||
| Allele | ||||
| G | 362 (90.5%) | 170 (85%) | 0.062 | |
| A | 38 (9.5%) | 30 (15%) | ||
| Genotypes | ||||
| GG | 164 (82%) | 72 (72%) | Dominant | 0.065 |
| AA + GA | 36 (18%) | 28 (28%) | ||
| Genotypes | ||||
| AA | 2 (1%) | 2 (2%) | Recessive | 0.603 |
| GG + GA | 198 (99%) | 98 (98%) | ||
| Genotypes | ||||
| GG + AA | 198 (99%) | 98 (98%) | Over-dominant | 0.603 |
| GA | 2 (1%) | 2 (2%) | ||
| IL28B (rs12979860) | ||||
| Genotype | ||||
| CC | 79 (39.5%) | 42 (42%) | Codominant | 0.878 |
| CT | 85 (42.5%) | 42 (42%) | ||
| TT | 36 (18%) | 16 (16%) | ||
| Allele | ||||
| C | 243 (60.8%) | 126 (63%) | 0.656 | |
| T | 157 (39.3%) | 74 (37%) | ||
| Genotypes | ||||
| CC | 79 (39.5%) | 42 (42%) | Dominant | 0.771 |
| TT + CT | 121 (60.5%) | 58 (58%) | ||
| Genotypes | ||||
| TT | 36 (18%) | 16 (16%) | Recessive | 0.787 |
| CC + CT | 164 (82%) | 84 (84%) | ||
| Genotypes | ||||
| CC + TT | 115 (57.5%) | 58 (58%) | Over-dominant | 1.000 |
| CT | 85 (42.5%) | 42 (42%) |
Abbreviations are same as in the text. n, number of patients in each group.