Table 1.

Clinical sample demographics for MR-seq data generation

Case	Number of regions	Region details	Age (years)	Gender	Comment
CRC1	6	Three primary, two LN met, one liver met	53	Female	MSS; KRAS mutant
CRC2	10	Three primary, three LN met, omental met, two liver met	44	Male	MSS
UBC	8	Three primary, three ureteral mass, three LN met	80	Male
RCC	9	Three primary, three IVC, three liver met	62	Female	IVC tumor thrombus
NSCLC	12	Three primary, three chest wall met, two+four LN met	66	Male

CRC, colorectal adenocarcinoma; IVC, inferior vena cava; KRAS, Kirsten RAS oncogene; LN, lymph node; MR-seq, multiregion sequencing; MSS, Microsatellite stable; NSCLC, non-small cell lung carcinoma; RCC, renal cell carcinoma; UBC, urothelial bladder carcinoma.