Table 3.
Frequency of symptoms at baseline.
| Symptom | Total sample (n = 61) | Intervention group (n = 31) | Control group (n = 30) | χ2 | P |
|---|---|---|---|---|---|
| Symptom severity | |||||
| Fatigue | 38 (62.3) | 18 (58.1) | 20 (66.7) | 0.480 | 0.488 |
| Dizziness | 24 (39.3) | 8 (25.8) | 16 (53.3) | 4.841 | 0.028 |
| Headache | 14 (23.0) | 8 (25.8) | 6 (20.0) | 0.291 | 0.590 |
| Fever | 10 (16.4) | 4 (12.9) | 6 (20.0) | – | 0.508a |
| Difficulty remembering | 37 (60.7) | 17 (54.8) | 20 (66.7) | 0.894 | 0.344 |
| Difficulty falling or staying asleep | 38 (62.3) | 18 (58.1) | 20 (66.7) | 0.480 | 0.488 |
| Blurred vision | 23 (37.7) | 10 (32.3) | 13 (43.3) | 0.796 | 0.372 |
| Rash, Itchy skin | 20 (32.8) | 8 (25.8) | 12 (40.0) | 1.394 | 0.238 |
| Ulcers or white spots in mouth | 20 (32.8) | 10 (32.3) | 10 (33.3) | 0.008 | 0.929 |
| Muscle and joint pain | 28 (45.9) | 13 (41.9) | 15 (50.0) | 0.399 | 0.527 |
| Numbness/tingling of hands or feet | 18 (29.5) | 9 (29.0) | 9 (30.0) | 0.007 | 0.934 |
| Decreased appetite | 14 (23.0) | 6 (19.4) | 8 (26.7) | 0.461 | 0.497 |
| Diarrhea | 31 (50.8) | 14 (45.2) | 17 (56.7) | 0.807 | 0.369 |
| Nausea or vomiting | 20 (32.8) | 7 (22.6) | 13 (43.3) | 2.980 | 0.084 |
| Fat redistribution | 18 (29.5) | 7 (22.6) | 11 (36.7) | 1.454 | 0.228 |
| Shortness of breath | 15 (24.6) | 8 (25.8) | 7 (23.3) | 0.050 | 0.823 |
| Perianal neoplasms | 12 (19.7) | 7 (22.6) | 5 (16.7) | 0.337 | 0.561 |
| Anxiety | 33 (54.1) | 12 (38.7) | 21 (70.0) | 6.011 | 0.014 |
| Depression | 36 (59.0) | 14 (45.2) | 22 (73.3) | 5.003 | 0.025 |
| Symptom distress | |||||
| Fatigue | 34 (55.7) | 15 (48.4) | 19 (63.3) | 1.380 | 0.240 |
| Dizziness | 21 (34.4) | 7 (22.6) | 14 (46.7) | 3.918 | 0.048 |
| Headache | 13 (21.3) | 7 (22.6) | 6 (20.0) | 0.061 | 0.806 |
| Fever | 9 (14.8) | 4 (12.9) | 5 (16.7) | – | 0.731a |
| Difficulty remembering | 33 (54.1) | 15 (48.4) | 18 (60.0) | 0.828 | 0.363 |
| Difficulty falling or staying asleep | 32 (52.5) | 15 (48.4) | 17 (56.7) | 0.419 | 0.517 |
| Blurred vision | 22 (36.1) | 9 (29.0) | 13 (43.3) | 1.352 | 0.245 |
| Rash, Itchy skin | 19 (31.1) | 8 (25.8) | 11 (36.7) | 0.838 | 0.360 |
| Ulcers or white spots in mouth | 15 (24.6) | 7 (22.6) | 8 (26.7) | 0.137 | 0.711 |
| Muscle and joint pain | 23 (37.7) | 11 (35.5) | 12 (40.0) | 0.132 | 0.716 |
| Numbness/tingling of hands or feet | 16 (26.2) | 8 (25.8) | 8 (26.7) | 0.006 | 0.939 |
| Decreased appetite | 13 (21.3) | 6 (19.4) | 7 (23.3) | 0.144 | 0.704 |
| Diarrhea | 28 (45.9) | 12 (38.7) | 16 (53.3) | 1.313 | 0.252 |
| Nausea or vomiting | 18 (29.5) | 6 (19.4) | 12 (40.0) | 3.124 | 0.077 |
| Fat redistribution | 18 (29.5) | 7 (22.6) | 11 (36.7) | 1.454 | 0.228 |
| Shortness of breath | 13 (21.3) | 7 (22.6) | 6 (20.0) | 0.061 | 0.806 |
| Perianal neoplasms | 10 (16.4) | 5 (16.1) | 5 (16.7) | – | 1.000a |
| Anxiety | 30 (49.2) | 11 (35.5) | 19 (63.3) | 4.731 | 0.030 |
| Depression | 35 (57.4) | 13 (41.9) | 22 (73.3) | 6.146 | 0.013 |
Note: Data are n (%). a Fisher’s exact test