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. 2021 Aug 2;8(4):453–469. doi: 10.1016/j.ijnss.2021.07.004

Table 1.

Summary table of evidence for quantitative studies (n = 21).

Study and location Aim of study Design, methods, and sample Key findings Quality score & limitation of study
You et al., 2015 [13] South Korea To identify reasons for MAE and why they are unreported and estimate the percentage of MAEs actually reported among hospital nurses.
  • Descriptive cross-sectional survey.

  • Questionnaire.

  • 312 nurses across three university hospitals.

  • Barriers perceived by nurses towards error reporting:

1) fear of blame associated with adverse health implications to patients; 2) an increased emphasis placed on MAE as benchmark to determine quality of delivered nursing care; 3) fear of adverse consequences associated with that error; 4) not wanting nursing administrators to hold them as solely responsible for the error instead of evaluating the medication system.
  • MMAT score: 100%

  • The use of convenience sampling might contribute to sample bias. The use of self-reporting methods might contribute to concerns of social desirability.

Chiang et al., 2010 [17] China To examine the factors that influence the failure to report medication adverse events by nurses.
  • Cross-sectional survey.

  • Questionnaire.

  • 872 nurses across five tertiary hospitals.

  • 337 (47%) participating nurses had failed to report self- or coworker-MAEs and 376 nurses (52.4%) had not failed to report.

  • Fear, perception of nursing quality, and nursing professional development were identified as barriers that contributed to failure to report by nurses.

  • Administration and reporting process were not identified as barriers of error reporting.

  • MMAT score: 100%

  • Potential social desirability effect in self-reported questionnaire. Convenience sample limits generalizability.

Qin et al., 2015 [34] China To analyze the behaviors of nurses toward reporting safety events, the barriers to reporting, and the correlations of these aspects with hospital safety culture.
  • Descriptive cross-sectional survey.

  • Questionnaire.

  • 1,125 nurses across eight hospitals.

  • Nurses' preferred reporting styles were as followed, informing leader” (63.0%–76.4%), informing doctor (41.8%–81.8%), “documentation” (49.1%–54.1%).

  • Managerial and collegial perception, and reporting procedures played as key barriers to error reporting.

  • Reasons for not reporting error as identified by nurses:

1) fear of receiving patients' complaint; 2) fear of being reprimanded; 3) fear of implication to future employment; 4)wanting to protect their colleagues; 5) fear that news will spread, and the press will write about it; 6) not wanting to be an incompetent nurse.
  • MMAT score: 75%

  • Use of convenience sampling limits generalizability. The use of self-reported questionnaire may contribute to potential response bias.

Hung et al., 2015 [35] China To explore the effects of nurses' attitudes and intentions regarding medication administration error reporting on actual reporting behaviour.
  • Descriptive cross-sectional survey.

  • Questionnaire.

  • 596 nurses who worked in general wards and intensive care units in a hospital.

  • The findings indicated that nurses' attitudes and intentions towards MAE reporting are positive, but the actual reporting rates are low.

  • Nurse managers' and co-workers’ attitudes are major factors contributing nurses' attitudes towards medication administration error reporting.

  • Nurses' attitudes also influenced their intention to report medication administration errors; however, no connection was found between intention and actual reporting behaviour.

  • MMAT score: 100%

  • Convenience sampling and data obtained from one hospital may not be representative. The need for participants to recall experiences for past three months may contribute to recall bias.

Yung et al., 2016 [36] China To explore the attitudes and perceived barriers to reporting medication administration errors and to understand the characteristics of – and nurses' feelings – about error reports.
  • Descriptive cross-sectional survey.

  • Questionnaire.

  • 306 nurses working in one large teaching hospital.

  • Nurses' possessed positive attitudes in error reporting. 88.9% prefer to engage in verbal reporting with head nurse (67.6%), colleagues (55.6%).

  • 83.0% of nurses experience self-recrimination after reporting, 63.4% experienced uneasiness if they choose not to report.

  • Barriers towards engaging in error reporting were:

1) fear of being distrusted by a patient and their family;
2) fear of administrators taking the error report as evidence to justify issuing a negative evaluation of the culpable staff; 3) fear of in patient–nurse disputes.
• Reasons for not reporting error were: 1) patients were not harmed (83.3%); 2) the error was not known to anyone except the involving personnel (45.1%).
  • MMAT score: 100%

  • Limit generalizability of findings due to study conducted in one hospital. Response bias owing to self-reporting.

Farag et al., 2017 [37] United States To examine the relationship among work environment, social capital and nurses' willingness to report medication errors.
  • Descriptive cross-sectional survey.

  • Questionnaire.

  • 71 nurses working in Emergency Department across five hospitals.

  • Most nurses (71.8%) were very likely to report errors with high potential for patient harm.

  • 54.9% of them were very likely to report errors that reached the patients but had no potential harm, and only 25.4% of nurses were very likely to report errors that were near missed.

  • Willingness of Emergency Department nurses to engage in reporting increases when feedback pertaining to the error committed was received, and when the manager adopted appropriate leadership style.

  • MMAT score: 50%

  • Findings is specific to one hospital and cannot be generalized. Potential social desirability effect in self-reported questionnaire

Mjadu & Jarvis 2018 [38] South Africa To describe the perceptions of registered nurses towards critical incident reporting in adult ICUs in three tertiary level provincial hospitals.
  • Non-experimental descriptive survey.

  • Questionnaire.

  • 127 nurses consist of ICU specialist and non-specialist of three hospitals.

  • While 50.5% had an effective attitude towards incident reporting, 63.4% of nurses had not reported any error for the past 12 months.

  • Despite nurses knew about the reporting system, major barriers towards error reporting as identified by nurses were: 1) collegial atmosphere of unpleasantness characterized by blame and punishment; 2)lack of confidentiality.

  • MMAT score: 75%

  • The nature of purposive sampling restricted to collection of data from one province may not be representative.

Afolalu et al., 2020 [39] Nigeria To compare doctors' and nurses' perceptions of factors influencing medical error reporting.
  • Descriptive cross-sectional survey.

  • Questionnaire.

  • 140 nurses and 90 physicians from one tertiary hospital.

  • The proportion of doctors (53.3%) not reporting error is higher as compared to nurses (39.3%).

  • Barriers of error reporting identified by nurses: 1) the emphasis of individual blame (79.6%); 2)lack of confidentiality (60.8%); 2)supervisor's inappropriate responses (58.7%); 4) patient's loss of trust (56.1%);

5) no point reporting that does not cause harm (53.7%).
  • Facilitators of error reporting identified by nurses: 1) clear guidelines about reporting of error (84.9%); 2) having role model who encourage reporting (81.1%);

3) getting feedback (70.5%).
  • MMAT score: 50%

  • Study was conducted on single site; hence findings might challenge generalizability.

Kim et al., 2011 [40] South Korea To identify the types of medication errors that occur in nursing practice and the nurses' perceptions of medication errors and reporting
  • Descriptive cross-sectional survey.

  • Questionnaire.

  • 220 nurses across seven hospitals.

  • Low reporting rate with only 28.3% of participants submit an incident report, despite 63.6% of participants had been involved in medication errors once or more in the past month.

  • Reasons for nurses not reporting errors were: 1) afraid of being a troublemaker (46.7%); 2)not aware of the importance of reporting, even in minor errors (25.0%); 3)wanting to cover up for the co-workers involved (10.9%).

  • MMAT score: 50%

  • Convenience sampling, low response rate and response bias may not be representative.

Chiang et al., 2019 [41] China To test the hypothesized model for hospital nurses' voluntariness of incident reporting and determine the extent which reporting culture factors, nursing safety practices, and work perceptions predict VIR.
  • Descriptive cross-sectional survey.

  • Questionnaire.

  • 1,380 nurses across six teaching hospitals.

  • More than half of nurses (nearly 60%) did not display voluntary attitude towards reporting of errors and near misses.

  • Nurses' voluntary incident reporting was influenced by reporting culture (collegial atmosphere of punishment, confidentiality, provision of feedback and learning from error), nursing safety practice, and perception of work (workload and job satisfaction).

  • MMAT score: 100%

  • The generalizability of findings may be limited due to data collected from the study population of six hospitals and self-reported data.

Rashed & Hamdan 2019 [42] Palestine To assess the attitudes of physicians and nurses toward incident reporting in Palestinian hospitals.
  • Descriptive cross-sectional survey.

  • Questionnaire.

  • 152 physicians and 323 nurses across 11 hospitals.

  • Physicians were 2.1 time more likely to report incidents than nurses.

  • Top three perceived barriers of incident reporting identified by nurses: 1)lack of feedback about reported medical errors (70.7%); 2)reporting is a method through which to pinpoint blame (67.2%); 3) lack of supervisor support to those who report error (50.5%.).

  • Top three fear of reporting consequences identified by nurses were: 1)fear of administrative sanctioning (77.7%); fear of malpractice litigation (72.4%); 3) fear that their own competence may be questioned (71%).

  • MMAT score: 75%

  • Self-reported survey findings may contribute to social desirability response bias, leading to overestimation of positive attitudes.

AbuAlRub et al., 2015 [43] Jordan To explore the awareness of the IR system, IR practices and barriers to IR among Jordanian staff nurses and physicians.
  • Descriptive exploratory survey.

  • Questionnaire.

  • 307 nurses and 144 physicians across seven hospitals.

  • Physicians were less likely to report any incident on 50% or more of occasions as compared to nurses.

  • Major barriers towards error reporting by nurses were:

1) felt pointless to report on near misses (69.0%); 2) not receiving any feedback (64.5%); 3) fear of receiving disciplinary actions (68.9%); 4) felt that reporting is unlikely to lead to system change (66.1%); 5) forgetting to report due to being busy (63.2%).
  • MMAT score: 50%

  • Convenience sampling and data obtained from seven hospital may not be representative.

Mansouri et al., 2019) [44] Iran To assess nurses' views about major barriers to reporting errors and adverse events in intensive care units.
  • Descriptive cross-sectional survey.

  • Questionnaire.

  • 251 nurses across seven hospitals

  • Majority of nurses (70.9%) failed to report errors despite having to commit them.

  • Three main areas that prevented nurses from reporting error were: 1)fear of consequences after reporting – fear of collegial blame, fear of reputation loss, and fear of being labelled as incompetent; 2) procedural barriers - lack of knowledge about the procedure, certain error considered as trivial, hence not reporting; 3) management barriers – blame culture, lack of feedback, facing of inappropriate reaction from manager.

  • MMAT score: 75%

  • Despite data gathered from seven hospital, modest sample size might challenge generalizability.

Toruner & Uysal 2012 [45] Turkey To determine the perspective of pediatric nurses regarding the causes, reporting, and prevention of medication errors.
  • Descriptive cross-sectional survey.

  • Questionnaire.

  • 119 pediatric nurses across four hospitals.

  • Despite majority of pediatric nurses (88%) made use of the error notification system, yet less than half (48%) of the errors were notified by nurses.

  • Top three barriers of error reporting for nurses were:

1) fear of potential blaming of nurses in case of adverse outcome for the patient (53%); 2)fear of losing credibility of the team (50%); 3) fear of disciplinary proceedings (42%).
  • MMAT score: 25%

  • Small sample size limits generalizability of findings.

Dirik et al., 2018 [46] Turkey To investigate hospital nurses' involvement in the identification and reporting of medication errors in Turkey.
  • Descriptive cross-sectional survey.

  • Questionnaire.

  • 135 nurses from one university hospital.

  • Nurses were reluctant to report error despite able to identify the errors. and when the error was reported, it is usually to physicians.

  • Common reasons why nurses not reporting error were:

1) afraid of being perceived as incompetent by their peers (71.9%); 2) fear of being punished by their managers (66.7%); 3) not aware of committing the error (66%); 4) patient was not harmed by the error (63.5%); 5) not wanting to facing negative reaction from patients & relatives (62.5%).
  • MMAT score: 75%

  • Findings is specific to one hospital and cannot be generalized.

Hammoudi et al., 2018 [47] Saudi Arabia To explore factors that influence the occurrence of MAEs and error reporting by nurses.
  • Descriptive cross-sectional survey.

  • Questionnaire.

  • 367 nurses working in five public hospitals.

  • Perceived barriers of error reporting by nurses were:

1) nurses felt reporting and contacting physicians were time consuming; 2) individuals blamed instead of the system by nursing administrator for its commission; 3) lack of positive feedback for correct medication administration; 5) focus predominantly placed on errors as determinant for quality of nursing care.
  • MMAT score: 75%

  • The use of convenience sampling may introduce non-response bias.

Moumtzoglou 2010 [48] Greece To explore the reasons why Greek nurses are reluctant to report adverse events.
  • Exploratory study.

  • Questionnaire.

  • 214 nurses across 14 hospitals.

  • Nurses' impeding factors for reporting of adverse events concerns with cultural aspect such as professional, national and organizational cultures, as well as structural issues of healthcare practices such as safety system, rules, and procedures.

  • The reasons cited by more than 50% of nurses for not reporting adverse events were:1)fear of the press; 2) fear that the error will be reported to nursing licensing board; 3)cumbersome of handling adverse event; 4)not confidence in bringing up the event; 5) fear of facing complaints by patients.

  • MMAT score: 100%

  • Moderate response rate (61%) might conceal sample bias due to the possibility of those who responded are individuals with certain interests in issues under study.

Nasiri et al., 2020 [49] Iran To determine factors affecting the failure to report medical errors in teaching hospitals affiliated to Iran.
  • Cross sectional descriptive analytical survey.

  • Questionnaire.

  • 131 nurses across two teaching hospitals.

Most important factors leading to failure to report medical errors as identified by nurses were:1) management related factor – lack of organizational support, failure to receive positive feedback, focusing on the person committing the error, inappropriate response of authorities relating to error severity; 2) nurse related factor – fear of legal issue, fear of being blamed by nursing authorities and physician, fear of incompetence stigma, fear of negative effects of error concerning economic losses; 3) factors related to reporting process – forgetting to report error, neglecting to report error, unclear definition of error.
  • MMAT score: 100%

  • The use of the classical numbers for scoring and prioritization.

Rutledge et al., 2018 [50] United States To report MER barriers among hospital nurses.
  • Descriptive cross-sectional survey.

  • Questionnaire.

  • 359 registered nurses of one community hospital.

Top four barriers of error reporting were:1) extra time involved in documenting a medication error (48.2%); 2) system for forms used to report medication errors are long and time-consuming (35.9%); 3) Fear of liability or lawsuits (34.3%); 4) Fear of being blamed (32.8%).
  • MMAT score: 50%

  • Findings based on one hospital could affect generalizability. Survey omits one item that examine managerial support.

Yang et al., 2020 [51] China To identify nurses' perceptions of patient safety emphasis, face-saving, power distance, and fear of medication error reporting and to explore face-saving and power distance as the underlying mechanisms for cultural factors in the relationship between nurses' perceptions of safety emphasis and fear of MER.
  • Cross-sectional descriptive and correlation.

  • Questionnaire.

  • 569 registered nurses across three tertiary teaching hospitals.

  • Nurses' fear of medication error reporting is strongly associated with their cultural background, especially face-saving (social esteem and social identity) and power distance (social hierarchy that defines disparity power between the subordinates and their superior).

  • When comparing the specific mediators' indirect effects, face-saving was found to be more powerful mediator than power distance.

  • MMAT score: 75%

  • Correlation data of this study impedes drawing of causality. Convenience sampling challenges generalizability of findings.

Lee et al., 2016 [52] China To identify which factors affect the intentions of nursing staff to report incidents using theory of planned behavior, organizational behavior.
  • Survey design.

  • Questionnaire.

  • 649 nurses across 40 large hospitals

Psychological safety, subjective norm and perceived behavioral control correlates with nurses' intention towards error reporting. 1)Psychosocial safety is characterized by just culture with no punishment when error was reported. 2) Perceived behavioral control characterized by nurses' possessing of sufficient knowledge, abilities, and resources. 3) Subjective norm was characterized by managerial and collegial response towards their reporting.
  • MMAT score: 75%

  • Possibility of sampling bias due to less than 60% response rate of completed survey.

Note: MAE = medication administration error. MMAT = Mixed Methods Appraisal Tool. VIR = voluntariness of incident reporting. IR = incident reporting.MER = medication error reporting.