TABLE 1.
Suppression of τ60 mutation by gene dosage
| Multicopy gene | Gene product | Suppression on:
|
|
|---|---|---|---|
| Minimal medium | Rich medium | ||
| TFC8 | τ60 | +++ | +++ |
| RPR1 | RNA component of RNase P (tRNA maturation) | − | − |
| NOP1 | Fibrillarin homolog (rRNA maturation) | − | − |
| FHL1 | Forkhead-like protein (rRNA maturation) | − | − |
| TFC3 | τ138, subunit of TFIIIC | − | − |
| TFC4 | τ131, subunit of TFIIIC | − | − |
| TFC1 | τ95, subunit of TFIIIC | ++ | − |
| TFC6 | τ91, subunit of TFIIIC | − | − |
| TFC7 | τ55, subunit of TFIIIC | − | − |
| BRF1 | Brf1/TFIIIB70, subunit of TFIIIB | − | − |
| SPT15 | TBP (TATA-binding protein), subunit of TFIIIB | ++ | + |
| TFC5 | B"/TFIIIB90, subunit of TFIIIB | ++ | − |