Skip to main content
. 2021 Oct 3;15:16. doi: 10.1186/s13030-021-00219-w

Table 1.

Example diseases and problems for which CBT is expected to be effective (Cochrane reviews)

Major disease conditions Summary of evidence Update

Psychiatric disorders:

Depression, general

‘Third -wave’ CBT as effective treatment of acute depression

Reduced depressive symptoms in dementia and mild cognitive impairment

Improved response and remission rates for treatment-resistant depression

Reduced depressive symptoms in children with long-term physical conditions

Reduced depressive symptoms in chronic obstructive pulmonary disease

Reduced depressive symptoms in dialysis patients

Reduced the number of sickness absence days in workers

October 2013

January 2014

May 2018

December 2018

March 2019

December 2019

October 2020

Anxiety, general

Obsessive–compulsive disorder

Panic disorder

Reduced anxiety symptoms in adults by “media-delivered CBT” (self-help)

Reduced anxiety symptoms in dementia and mild cognitive impairment

Reduced anxiety symptoms in adults by therapist-supported internet CBT

Reduced anxiety symptoms in children with long-term physical conditions

Effective for attention control in children and adolescents

Effective in children and adolescents with this disorder

Effective in adults with this disorder

Efficacy of both CBT alone and CBT and antidepressants

Efficacy of both CBT and benzodiazepines

September 2013

January 2014

March 2016

December 2018

November 2020

October 2006

April 2007

January 2007

January 2009

Post-traumatic stress disorder (PTSD)

Social anxiety disorder

Effective in children and adolescents for up to 1 month following CBT

Reduced clinician-assessed PTSD symptoms in adults

Reduced PTSD symptoms when used as couple and family therapies

Reduced social phobia via brief CBT

December 2012

December 2013

December 2019

September 2018

Acute stress disorder Reduced acute traumatic stress symptoms via brief trauma-focused CBT March 2010
Attention deficit–hyperactivity disorder Beneficial for treating adults with this disorder in the short term March 2018

Bulimia nervosa

Hypochondriasis

Somatoform disorder

Efficacy of a specific manual-based form of CBT for bulimia nervosa

Reduced hypochondriacal symptoms and general functioning

Reduced symptom severity in adults with somatoform disorders

October 2009

October 2007

November 2014

Physical diseases:

Breast cancer

Improved survival at 12 months (metastatic)

Favorable effects on anxiety, depression and mood disturbance (non-metastatic)

June 2013

May 2015

Chronic fatigue syndrome

Fibromyalgia

Reduced fatigue symptoms

Reduced pain, negative mood, and disability

July 2008

September 2013

Irritable bowel syndrome

Recurrent abdominal pain

Reduced symptoms of irritable bowel syndrome and improved quality of life

Reduced pain in the short term in children and adolescents

January 2009

January 2017

Tinnitus Reduced negative impacts on quality of life and depression January 2020

Behavioral and other problems:

Antisocial behaviors

Benzodiazepine use

Burden of care for dementia

Early behavioral problems

Needle-related problems

Obesity and overweight

Occupational stress

Problem gambling

Self-harm

Sexual abuse

Reduced antisocial behaviors in young people in the short term

Effective in the short term for reducing benzodiazepine harmful use

Reduced psychological stress in family caregivers of people with dementia

Improved child conduct problems, parental mental health, and parenting skills

Reduced children’s needle-related pain and distress in children and adolescents

Reduced weight, predominantly useful when combined with diet and exercise

Reduced stress at work in healthcare workers

Reduced pathological and problem gambling behaviors immediately after CBT

Resulted in fewer adults repeatedly self-poisoning and self-injuring

Reduced symptoms of PTSD, anxiety, and depression in children

October 2007

May 2015

November 2011

February 2012

October 2018

April 2005

April 2015

November 2012

May 2016

May 2012

Smoking Effective for smoking cessation in indigenous populations January 2012