Table 5.

Uncovering potential new DDIs from the 1D-CNN model

Drug1	Drug2	Side effect (SE)	SE freq (%)	Probability			Proof
				Random	One-unseen	Both-unseen
Bupropion	Benazepril	Heart attack	25.8	0.951	–	0.182	e-1
Didanosine	Stavudine	Acidosis	13.6	0.872	0.068	–	2-2
Bupropion	Fluoxetine	Panic attack	10.5	0.868	0.100	–	e-3
Bupropion	Orphenadrine	Muscle spasm	24.2	0.865	0.161	–	e-4
Tramadol	Zolpidem	Diaphragmatic hernia	1.4	0.854	0.029	0.041	e-5
Paroxetine	Fluticasone	Muscle spasm	24.2	0.871	0.355	–	e-6
Paroxetine	Fluticasone	Fatigue	38.2	0.863	0.450	–	e-7
Fluoxetine	Methadone	Pain	37.6	0.769	–	–	e-8
Carboplatin	Cisplatin	Blood sodium decreased	23.1	0.749	0.097	0.080	e-9
Chlorthalidone	Fluticasone	High blood pressure	30.5	0.797	0.439	–	e-10

The table shows the drug–drug potential side effects supported with the existence probability predicted with the literature link proof