Figure 3.

Occurrence of GATA2 ASE in AML subgroups. (A) Bar plot indicating the percentage of cases with GATA2 ASE in each mutational subgroup. The color of the bars indicates the strength of the association as log₁₀ (P value), with a sign determined by the nature of the association. The scale ranges from blue for negative associations to red for positive associations. The dotted horizontal line indicates the percentage of cases with GATA2 ASE in the whole AML cohort. (B) Circos plot indicating the cooccurrence of mutations in AML and GATA2 ASE. (C) Bar plots for each patient with CEBPA DM showing GATA2 ASE, observed by the discrepancy between VAF at the DNA level and VAF at the RNA level. *Indicates significance at a false discovery rate <0.05 in a χ² test.