A, Fatty acid binding protein 3 (FABP3) levels positively correlated with the severity of peripheral arterial disease (PAD). A bar chart representing mean values with confidence intervals for FABP3 levels in control patients without PAD (n = 75; 1.3 ≤ ankle-brachial index [ABI] ≤ 0.9), patients with PAD (n = 70; ABI <0.9), and non-compressible tibial vessels (n = 5; noncompressible; ABI ≥ 1.3). Levels of FABP3 demonstrated an increase in FABP3 levels as severity of PAD worsen. B, The relationship between values for ABI and FABP3. Levels of FABP3 were compared between patients with PAD (n = 21; squares; ABI < 0.9) and patients without PAD (n = 21; circles; 1.3 ≤ ABI ≤ 0.9) after matching for age, sex, and risk factors (age, sex, coronary artery disease, hypercholesteremia, hypertension, smoking history, and diabetes). FABP3 values were inversely correlated to the ABI using spearmen correlation (r = –0.51; P = .001).