Supplementary Table.
Liver and kidney function blood test resultsa
| Biochemistry test | E-selectin/AAV | LacZ/AAV | PBS (no virus) | P value | Normal range |
|---|---|---|---|---|---|
| AST, U/L | 123 | 118 | 117 | .91 | 50-270 |
| ALT, U/L | 32 | 40 | 67 | .1 | 29-77 |
| ALP, U/L | 29 | 33 | 31 | .84 | 51-285 |
| Bilirubin, mg/dL | |||||
| Total | 0.5 | 0.5 | 0.8 | .21 | 0.1-0.9 |
| Direct | 0.5 | 0.5 | 0.8 | .46 | 0.1-0.9 |
| Albumin, g/dL | 1.6 | 1.9 | 1.6 | .17 | 2.5-2.8 |
| BUN, mg/dL | 23 | 24 | 21 | .24 | 18-29 |
| Creatinine, mg/dL | 0.1 | 0.2 | 0.1 | .27 | 0.1-0.4 |
AAV, Adeno-associated virus; ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BUN, blood urea nitrogen; PBS, phosphate-buffered saline.
a
Intracardiac blood samples were taken before animal sacrifice; no differences were found among mice treated with E-selectin/AAV (n = 4), LacZ/AAV (n = 7), or PBS (no virus; n = 5) via analysis of variance statistical analysis.