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. 2020 Apr 23;1:69–80. doi: 10.1016/j.jvssci.2020.04.001

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This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig 6 — Histologic analysis. Panel 1, Representative histologic images of H1 to H5 sections collected from different abdominal aortic aneurysm (AAA) areas in control swine showing developing neointimal hyperplasia, inflammation, smooth muscle cell proliferation (H4; arrows), adventitial thickening and neovascularization, and elastin degradation. Az, Representative Alizarin Red S (Az) stain showing extensive calcification (red) of AAA media and adventitia. Panel 2, Representative histologic images of H1 to H5 sections collected from AAA areas in 1,2,3,4,6-pentagalloylglucose (PGG)-treated swine showing apparently diminished hyperplasia and no calcification (Az). Panel 3, Representative histologic images of remote organs from PGG-treated swine showing unaffected normal structures of myocardium (a), liver (b), kidney (c), lung (d), brain (e), and spleen (f). All sections (except for Az) were stained with elastica-Masson, which revealed collagen (blue), elastin (dark brown), and cells (red).