Fig 2.

Maximum diameter of suprarenal aortas of mice at day 28 measured by ultrasound examination in non–angiotensin II (AngII)–infused mice (control [con], n = 6; control plus metformin [con+met], n = 3), mice infused with AngII with (n = 11) and without (n = 12) metformin (met) treatment. Data presented as individual measurements with the mean and analyzed using analysis of variance adjusted using the Fisher least significant difference test (∗P < .05; ∗∗∗P < .001). Dashed line indicates threshold of 50% increase in aortic diameter from that of the control mice.