Table 1.
Baseline clinical characteristics of patients with critical COVID-19
| Variables | Total | No infections | Infections | p-value |
|---|---|---|---|---|
| (N = 321)* | (N = 254) | (N = 67) | ||
| Age, years | 61.4 (51.4–72.9) | 61.6 (52.3–73.7) | 59.1 (48.7–72.5) | 0.451 |
| Male sex | 229, 71.3% | 180, 70.9% | 49, 73.1% | 0.763 |
| African/Black | 213, 66.4% | 164, 64.6% | 49, 73.1% | 0.669 |
| Comorbid conditions | ||||
| Diabetes mellitus | 154, 48.0% | 128, 50.4% | 26, 38.8% | 1.000 |
| Hypertension | 184, 57.3% | 149, 58.7% | 35, 52.2% | 0.405 |
| CKD | 41, 12.8% | 32, 12.6% | 9, 13.4% | 1.000 |
| Cancer | 13, 4.0% | 8, 3.1% | 5, 7.5% | 0.155 |
| Baseline inflammatory markers on admission to critical care | ||||
| Lymphocytes, 109/L | 1.0 (0.7–1.3) | 1.0 (0.7–1.3) | 0.9 (0.7–1.4) | 0.908 |
| CRP, mg/L | 108.0 (56.5–181.5) | 106.0 (53.0–180.0) | 124.0 (78.5–220.0) | 0.046 |
| Ferritin, ng/ml (n = 253) | 932.0 (353.7–1531.0) | 910.0 (349.0–1483.0) | 1019.5 (386.0–1663.0) | 0.585 |
| Lactate, mmol/L (n = 88) | 1.6 (1.2–2.1) | 1.6 (1.2–2.1) | 1.7 (1.5, 2.1) | 0.527 |
| PCT, ng/ml | 0.2 (0.1–0.4) | 0.2 (0.1–0.4) | 0.2 (0.1–0.5) | 0.806 |
⁎
Continuous variables are expressed as median (interquartile range); categorical variables are expressed as n, %.
Abbreviations: CKD, chronic kidney disease; CRP, C-reactive protein; PCT, procalcitonin