Fig. 4.
Schematic diagram of Molecular-Biology Chromatography(MBC) and Cell Membrane Chromatography(CMC). MBC uses enzymes, receptors, DNA, transporters in plasma, and other biomacromolecules with essential physiological functions as stationary phases to separate and purify active compounds. CMC adsorbs the cell membrane containing specific receptors on the surface of SiO2. The self-fusion characteristics of living cell phospholipids and the strong binding characteristics of silicon hydroxyl (Si–OH) on SiO2 form the cell membrane stationary phase, which can identify the specific targets in complex samples that produce the biological effects of ligands.