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Narrow Therapeutic Index (NTI) and cannabinoid medications with protein binding ≥85%
| NTI medications | Protein binding ≥85% |
|---|---|
| amphotericin B | >90 |
| cannabidiola, b | >94 |
| cyclosporine | 90 |
| dronabinola, b | 97 |
| levothyroxine | >99 |
| nabilonea, b | Highlyc |
| nabiximolsa, b | >94 |
| phenytoin | 90 |
| quinidine | 88 |
| tacrolimus | >99 |
| valproic acid | 85 |
| warfarin (VKA) | 99 |
VKA, vitamin K antagonist; PI, prescribing information.
Not considered an NTI.
Cannabinoid medication.
As defined by nabilone (Cesamet®) PI.
