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Smoking INDUCES the metabolism of NTI medications that serve as a CYP1A2 enzyme SUBSTRATE
| acenocoumarol (VKA) |
| aminophylline |
| amiodarone |
| amitriptyline |
| carbamazepine |
| clomipramine |
| clonidine |
| cyclobenzaprine |
| desipramine |
| doxepin |
| imipramine |
| mephenytoin |
| nortriptyline |
| pimozide |
| theophylline |
| warfarin (VKA) |
VKA, vitamin K antagonist; NTI, Narrow Therapeutic Index.
