Table 4.
Stratified Continuous Models of Non-Exercise Estimated Cardiorespiratory Fitness (METs) in the NIH-AARP Diet and Health Study of Men and Women (N=330,769).
| Age (years) | Body Mass Index (kg/m2) | Smoking Status | Physical Activity | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||||
| 50-60 | 61-71 | 18.5-24.9 | 25-29.9 | ≥30 | Never | Former | Current | Never or rarely and 1-3 times per month | 1-2 times per week | 3-4 times per week | 5 or more times per week | |
| HR 95% (CI) All-cause mortality-men |
0.85 (0.83-0.87) |
0.85 (0.84-0.86) |
0.85 (0.83-0.87) |
0.87 (0.85-0.88) |
0.85 (0.83-0.87) |
0.89 (0.86-0.91) |
0.86 (0.85-0.88) |
0.89 (0.87-0.92) |
0.81 (0.76-0.86) |
0.88 (0.84-0.92) |
0.84 (0.79-0.9) |
0.83 (0.77-0.9) |
| HR 95% (CI) All-cause mortality-women |
0.85 (0.82-0.88) |
0.84 (0.82-0.85) |
0.83 (0.81-0.86) |
0.83 (0.8-0.86) |
0.87 (0.84-0.9) |
0.9 (0.87-0.92) |
0.85 (0.83-0.88) |
0.86 (0.83-0.89) |
0.75 (0.7-0.8) |
0.89 (0.83-0.95) |
0.82 (0.73-0.92) |
0.83 (0.71-0.96) |
|
| ||||||||||||
| HR 95% (CI) CVD mortality-men |
0.8 (0.75-0.86) |
0.86 (0.83-0.89) |
0.85 (0.8-0.91) |
0.88 (0.84-0.93) |
0.82 (0.78-0.87) |
0.83 (0.77-0.89) |
0.85 (0.82-0.89) |
*0.96 (0.89-1.04) |
0.68 (0.59-0.79) |
0.82 (0.73-0.92) |
0.76 (0.64-0.9) |
0.8 (0.65-0.97) |
| HR 95% (CI) CVD mortality-women |
0.81 (0.74-0.9) |
0.86 (0.81-0.89) |
0.84 (0.78-0.9) |
0.83 (0.78-0.9) |
0.88 (0.82-0.94) |
0.91 (0.85-0.97) |
0.84 (0.79-0.9) |
0.85 (0.78-0.93) |
0.8 (0.68-0.95) |
0.85 (0.72-0.99) |
*0.84 (0.63-1.1) |
*0.87 (0.62-1.2) |
|
| ||||||||||||
| HR 95% (CI) Cancer mortality-men |
0.89 (0.86-0.93) |
0.89 (0.87-0.91) |
0.9 (0.87-0.94) |
0.92 (0.89-0.94) |
0.86 (0.83-0.9) |
0.92 (0.87-0.96) |
0.91 (0.88-0.94) |
0.94 (0.9-0.99) |
0.8 (0.72-0.9) |
0.86 (0.8-0.93) |
0.8 (0.72-0.9) |
0.85 (0.75-0.97) |
| HR 95% (CI) Cancer mortality-women |
0.91 (0.87-0.96) |
0.89 (0.85-0.91) |
0.9 (0.86-0.94) |
0.87 (0.82-0.91) |
0.9 (0.86-0.96) |
0.94 (0.89-0.99) |
0.92 (0.88-0.97) |
0.91 (0.86-0.96) |
0.76 (0.67-0.86) |
0.87 (0.77-0.97) |
0.72 (0.59-0.86) |
0.78 (0.61-0.99) |
CVD; cardiovascular disease, CI; confidence intervals, HR; hazard ratio expressed per 1-MET (metabolic equivalent) increase. All risk models were statistically significant (p<0.05) except models with *, where statistical significance was not reached. Risk models were adjusted for race ethnicity, marital status, education level, age, body mass index, first-degree relatives with history of cancer, diabetes, hypertension, dyslipidemia, smoking status, total alcohol drinks per day, total energy intake, fibers intake, fruits intake, vegetables intake, red meat intake and menopausal status for women only.