Fig.6.

In spinal intact (SI) lightly anesthetized male mouse voiding occurs at the maximum pressure in the bladder (CMG trace) correlating with prominent bursting of the EUS (EMG trace, upper left panel). In a spinalized (SCI) male mouse bursting and reflex voiding partially recovered 4 weeks post-transection at T10 (lower left panel). EUS bursting in an intact female mouse is less prominent compared to the level of tonic activity and to bursting in the male (upper right panel). In SCI female mice EUS bursting does not recover 5 weeks post-transection; instead it is substituted by brief EUS relaxations occurring at the peak of BL pressure (lower right panel. Time scale in all plots in the same, but the ratio between scales of EMG in the left and right columns is 10:1.