Figure 2.
Adenocarcinoma: (a) Smear shows atypical cells (MGG 400x) with cytoplasmic PAD staining (400x) (inset), (b) CB shows acini of tumour cells (H and E 200x), (c and d) Positive CK7 and TTF1 (IHC 200x); Squamous cell carcinoma: (e) Smear (MGG 400x) and CB (H and E 400x) show atypical polygonal epithelial cells (MGG 400x), (g and h) Positive CK5/6 (IHC 200x) and p63 (IHC 400x); Small cell carcinoma: (i and j) Smear (MGG 100x) and CB (H and E 200x) show round to ovoid tumour cells with nuclear moulding, (k) Positive Synaptophysin and Chromogranin (inset) (IHC 200x), (l) Ki-67 ~70% (IHC 200x)
