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. 2021 Oct 4;16(10):e0257981. doi: 10.1371/journal.pone.0257981

Table 3. Prognostic factors associated with HRQOL in the total population including both KT and CKD patients a.

Parameter Higher SF-36 score Higher CKD-targeted score
Estimate (95% C.I) SE P Estimate (95% C.I.) SE P
KT (vs. CKD) 8.760 (5.290, 9.414) 1.041 < .0001 0.428 (-1.102, 1.941) 0.735 0.561
Time -1.457 (-3.585, 1.408) 1.450 0.315 -0.462 (-2.902, 2.289) 1.333 0.729
eGFR 0.028 (-0.055, 0.058) 0.015 0.058 0.037 (0.011, 0.058) 0.012 0.003
Age -0.011 (-0.085, 0.028) 0.034 0.753 -0.031 (-0.064, 0.026) 0.027 0.236
Gender (Male) 0.032 (-1.358, 1.422) 0.789 0.083 1.024 (0.085, 2.134) 0.566 0.040
Hypertension -1.367 (-3.035, 0.714) 1.054 0.195 -0.156 (-1.495, 1.082) 0.818 0.849
Diabetes mellitus -4.662 (-5.829, -2.501) 0.881 < .0001 -3.035 (-4.127, -1.353) 0.683 < .0001
Cardiovascular Ds -3.683 (-6.471, -0.257) 1.561 0.018 -2.634 (-4.537, -0.195) 1.211 0.030
Cerebrovascular Ds -4.121 (-7.405, -1.120) 1.787 0.021 -3.511 (-6.578, -0.903) 1.387 0.011
BMI -0.079 (-0.292, 0.134) 0.109 0.524 -0.047 (-0.222, 0.127) 0.089 0.594
Albumin 1.357 (-0.754, 3.467) 1.076 0.208 1.381 (-0.147, 3.015) 0.705 0.075
Hemoglobin 1.153 (0.544, 2.337) 0.230 < .0001 0.704 (0.423, 1.047) 0.178 < .0001
Marriage 3.585 (1.766, 5.341) 1.021 0.0004 4.818 (3.411, 6.190) 0.792 < .0001
Higher education b 2.965 (1.000, 3.750) 0.771 0.010 0.085 (-0.981, 1.150) 0.598 0.876
Higher income c 3.249 (1.980, 4.725) 0.904 0.0003 2.164 (1.414, 3.735) 0.701 0.002
Employment 3.899 (2.243, 5.203) 0.789 < .0001 6.731 (5.384, 7.613) 0.612 < .0001
Health insurance (vs. Health care) 4.962 (1.313, 9.083) 1.657 0.003 3.602 (0.569, 5.899) 1.285 0.017

BMI, body mass index; C.I., confidence interval; CKD, chronic kidney disease; Ds, Disease; eGFR, estimated glomerular filtration rate by MDRD equation; KT, kidney transplantation; SE, standard error.

a Generalized estimated equation analysis was performed.

bHigher education was defined as receiving a diploma from college or higher.

c Higher income was defined as monthly income above $ 4,500. P value by generalized estimated equation analysis.