Fig 9. The PS-VAE enables a detailed brain region-to-behavior mapping in the two-view mouse dataset.

A: PS-VAE latents (gray traces) and their predictions from neural activity (colored traces) recorded across dorsal cortex with widefield calcium imaging. Vertical dashed black lines delineate individual test trials. See S26 Video for a video of the full frame decoding. B: The behavioral specificity of the PS-VAE can be combined with the anatomical specificity of computational tools like LocaNMF [19] to produce detailed mappings from distinct neural populations to distinct behavioral features. Region acronyms are defined in Table 1. C: VAE latents (gray traces) and their predictions from the same neural activity as in A (black traces). The distributed behavioral representation produced by the VAE does not allow for the same region-to-behavior mappings enabled by the PS-VAE.