Table 2.
Multivariate analyses on overall survival in colon cancer.
| Characteristics | Overall survival | ||
|---|---|---|---|
| HR (95% CI) | SE | p-value | |
| Race | <0.001 | ||
| White | Reference | ||
| Black | 1.196 (1.161–1.232) | 0.015 | <0.001 |
| Other | 0.780 (0.750–0.812) | 0.020 | <0.001 |
| Age at diagnosis | <0.001 | ||
| ≤75 years | Reference | ||
| >75 years | 2.524 (2.474–2.576) | 0.010 | |
| Histology | 0.005 | ||
| Adenocarcinoma | Reference | ||
| Mucinous/signet ring cell | 1.042 (1.013–1.072) | 0.015 | |
| T stage | <0.001 | ||
| T3 | Reference | ||
| T4 | 1.650 (1.611–1.689) | 0.012 | |
| N stage | <0.001 | ||
| N0 stage (<4 lymph nodes) | Reference | ||
| N0 stage (<8 lymph nodes) | 0.810 (0.759–0.864) | 0.033 | <0.001 |
| N0 stage (<12 lymph nodes) | 0.690 (0.649–0.733) | 0.031 | <0.001 |
| N0 stage (≥12 lymph nodes) | 0.541 (0.512–0.572) | 0.028 | <0.001 |
| N1 stage | 0.909 (0.860–0.962) | 0.029 | 0.001 |
| N2 stage | 1.389 (1.311–1.471) | 0.029 | <0.001 |
| Tumor grade | <0.001 | ||
| High/Moderate | Reference | ||
| Poor/Anaplastic | 1.147 (1.122–1.172) | 0.011 | <0.001 |
| Unknown | 1.131 (1.059–1.208) | 0.033 | <0.001 |
| Sex | <0.001 | ||
| Male | Reference | ||
| Female | 0.839 (0.824–0.855) | 0.010 | |
| Year of diagnosis | 0.547 | ||
| 2004–2007 | Reference | ||
| 2008–2010 | 1.006 (0.986–1.026) | 0.010 | |
| Chemotherapy | <0.001 | ||
| No | Reference | ||
| Yes | 0.586 (0.572–0.600) | 0.012 | |