Table 4.

Factors associated with intraoperative positive CTCs in colorectal cancer patients in T1 and T2 based on univariate and multivariate analyses.

	T1	T2
	Univariate Analysisa	Univariate Analysisa	Multivariate Analysisb
Independent variables	p-value	p-value	Odds ratio	95%CI	p-value
Sex
Female vs Male	0.35	0.049	0.11	0.02–0.76	0.03
Preoperative chemotherapy	0.26	0.55
Preoperative radiochemotherapy	0.06	0.39
Preoperative radiotherapy	0.40	0.27
T stage
T1 vs T2 vs T3 vs T4	0.82	0.73
Lymphovascular invasion
Yes vs No	1.01	0.72
Stage
Stage I vs II vs III vs IV	0.84	0.36
Vascular invasion
Yes vs No	1.01	0.03			NS
Perineural invasion
Yes vs No	1	0.71
Metastatic disease
Yes vs No	1.01	0.25
Tumor grade
Grade 1 vs Grade 2 vs Grade 3	0.28	0.44
Tumor location
Colon vs rectum	0.20	0.04	9.18	1.22–69.02	0.01
Positive lymph nodes
0–1 vs > 1	0.74	0.04			NS

^aChi-square test or Fisher’s exact test when appropriate; ^b Multivariate logistic regression; Hosmer–Lemeshow p = 0.22 (>0.05).

CI, confidence interval; NS, not significant.