Table 3.
Comparison of IVF results obtained in the four study groups.
| Group 1 Age ≤39 years normal DNA fragmentation |
Group 2 Age ≤39 years altered DNA fragmentation |
Group 3 Age ≥40 years normal DNA fragmentation |
Group 4 Age ≥40 years altered DNA fragmentation |
|
|---|---|---|---|---|
| N | 52 | 32 | 49 | 30 |
| Number of oocytes retrieved | 8.3±3.8 | 8.2±4.3 | 7.8±3.5 | 8.0±3.9 |
| Number of mature oocytes retrieved (MII) | 6.2±2.4 | 6.0±3.2 | 5.9±4.0 | 6.0±3.3 |
| Fertilization rate | 283/321 (88%) | 165/194 (85%) | 24/287 (86%) | 150/182 (82%) |
| Blastocyst formation rate | 178/283 (63%)a | 83/194 (43%)b | 172/287 (60%)a | 75/182 (41%)b |
| Expanded blastocyst formation rate | 119/283 (42%)a | 41/194 (21%)b | 115/287 (40%)a | 33/182 (18%)b |
| Clinical pregnancy rate | 22/52 (42%) | 12/32 (38%) | 19/49 (39%) | 11/30 (37%) |
| Multiple pregnancy rate | 1/52 (1%) | 0/32 (0%) | 0/49 (0%) | 0/30 (0%) |
| Miscarriage rate | 1/22 (5%)a | 3/12 (25%)b | 1/19 (5%)a | 5/11 (46%)b |
| Ongoing pregnancy rate | 21/52 (40%) | 9/32 (28%) | 18/49 (37%) | 6/30 (20%) |
a,b
Values with different letters inside the line differ significantly (p<0.05).