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. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Addict Behav. 2021 Jun 29;122:107031. doi: 10.1016/j.addbeh.2021.107031

Table 3.

Final model of effects between PTSD, PTSD symptom clusters, and pain predicting AUD symptomology. Estimates are displayed as β [95% Confidence Interval].

Variable Model 1 PTSD and pain main effects Model 2 PTSD and pain interaction Model 3 PTSD symptom cluster and pain main effects Model 4 PTSD symptom cluster and pain interactions
Co-variates
 Intercept 21.778 [18.08, 25.48] 22.19 [18.55, 25.83] 21.76 [18.08, 25.45] 22.48 [18.85, 26.11]
 Age −0.10 [−0.19, −0.01] −0.08 [−0.17, 0.01] −0.10 [−0.19, −0.01] −0.08 [−0.17, 0.01]
 Sex −7.07 [−8.13, −6.01] −6.91 [−7.90, −5.98] −6.84 [−8.00, −5.88] −6.86 [−7.90, −5.81]
 White (ref) REF REF REF REF
 Hispanic −0.11 [−1.24, 1.02] −0.03 [−1.15, 1.08] −0.25 [−1.38, 0.88] −0.17 [−1.28, 0.95]
 Black 1.11 [−0.14, 2.15] 1.32 [−0.09, 2.35] 0.87 [−0.37, 2.12] 0.89 [−0.33, 2.11]
 Other race −3.99 [−6.00, −1.98] −3.61 [−5.59, −1.63] −4.02 [−6.02, −2.02] −3.61 [−5.58, −1.64]
 Combat exposure 4.70 [3.27, 6.12] 3.84 [2.41, 5.27] 4.59 [3.15, 6.02] 3.54 [2.10, 4.99]
PCL-5 total score 0.10 [0.08, 0.13] 0.11 [0.09, 0.14]
Pain 0.05 [0.04, 0.06] 0.06 [0.05, 0.07] 0.05 [0.04, 0.06] 0.06 [0.05, 0.08]
PTSD symptom clusters
 Re-experiencing 0.38 [0.23, 0.53] 0.41 [0.30, 0.52]
 Avoidance −0.004 [−0.26, 0.26] 0.04 [−0.20, 0.28]
 Negative cognitions/mood 0.18 [0.06, 0.30]
 Hyperarousal −0.19 [−0.35, −0.04]
Interactions
 PTSD* Pain −0.002 [−0.003, −0.002]
 Re-experiencing* Pain −0.004 [−0.007, 0.000]
 Avoidance* Pain −0.01 [−0.02, −0.01]

Note: Ref=reference group for self-reported race/ethnicity covariate (White is reference group). In model 1 we entered main effects of PTSD (PCL-5 scores) and pain (POQ scores) as well as all covariates. In model 2 we entered overall PTSD (PCL-5 scores) interacting with pain (POQ scores) as well as all covariates. In model 3 we entered main effects of PTSD symptom clusters (PCL-5 subscale scores) and pain (POQ scores). In model 4 we entered a taxonomy of interactions between PTSD symptom clusters (PCL-5 subscale scores) and pain (POQ scores). For parsimony, interactions that were not significant were removed. Values above represent our final model of PTSD symptom clusters and pain predicting alcohol use disorder (AUDIT scores).

BOLD = confidence interval does not include 0