Table 5.

Associations between sarcopenia and pretransplant LT-VLA disability and waitlist delisting or death

	Pretransplant Disability	Waitlist Delisting or Death
Definition	Regression Estimate (95% CI)	Hazard Ratio (95% CI)
EWGSOP2
Limited	0.20* (−0.0001 to 0.41)	2.84 (0.94 to 8.55)
Expanded	0.25† (−0.0004 to 0.51)	1.25 (0.25 to 6.10)
FNIH
Limited	−0.03 (−0.24 to 0.18)	0.98 (0.26 to 3.70)
Expanded	0.16 (−0.12 to 0.45)	1.00 (0.12 to 8.21)
Lowest Quartile
Limited	0.07 (−0.09 to 0.23)	3.75‡ (1.42 to 9.93)
Expanded	0.23‡ (0.01 to 0.44)	3.46‡ (1.09 to 10.97)

Definition of abbreviations: CI = confidence interval; EWGSOP2 = European Working Group on Sarcopenia in Older People 2; FNIH = Foundation for the National Institutes of Health; Lowest Quartile = distribution-based lowest quartile of sarcopenic study participants; LT-VLA = Lung Transplant-Specific Valued Life Activities Disability Scale.

Associations between sarcopenia and pretransplant disability evaluated using linear regression. LT-VLA MID = 0.3. Associations between sarcopenia definitions and composite outcome of waitlist delisting or death evaluated using Cox proportional hazards models. One patient who was enrolled after transplant was excluded from Cox analyses. All analyses adjusted for age, sex, race, and diagnosis.

^*P = 0.0501.

^†P = 0.054.

^‡Statistically significant at P < 0.05.