Table 2.
Group | Hair | Activity | Intake | Faeces | Urine | Death | Body weight (g, Mean ± SD) | |
---|---|---|---|---|---|---|---|---|
Cisplatin + oe-NC | Day 0 ~ 6 | Bright and clean | Normal | Normal | Normal | Normal | NO | 20.53 ± 1.87 |
Day 9 | Bright and clean | Normal | Normal | Normal | Normal | NO | 20.96 ± 2.13 | |
Day 12 | Bright and clean | Normal | Normal | Normal | Normal | NO | 20.21 ± 1.71 | |
Day 15 | Dull and messy | Reduce | Reduce | Reduce | Reduce | NO | 19.23 ± 2.25 | |
Day 18 | Dull and messy | Reduce | Reduce | Reduce | Reduce | NO | 17.53 ± 2.34 | |
Day 21 | Dull and messy | Reduce | Reduce | Reduce | Reduce | NO | 16.05 ± 1.96 | |
Day 24 | messy and Dry | Reduce | Reduce | Reduce | Reduce | NO | 14.28 ± 2.73 | |
Cisplatin + oe-KLF2 + oe-NC | Day 0 ~ 6 | Bright and clean | Normal | Normal | Normal | Normal | NO | 21.19 ± 2.36 |
Day 9 | Bright and clean | Normal | Normal | Normal | Normal | NO | 20.87 ± 1.92 | |
Day 12 | Bright and clean | Normal | Reduce | Reduce | Reduce | NO | 20.16 ± 2.54 | |
Day 15 | Dull and messy | Reduce | Reduce | Reduce | Reduce | NO | 19.38 ± 1.78 | |
Day 18 | Dull and messy | Reduce | Reduce | Reduce | Reduce | NO | 18.04 ± 2.21 | |
Day 21 | Dull and messy | Reduce | Reduce | Reduce | Reduce | NO | 16.72 ± 2.45 | |
Day 24 | Messy and Dry | Reduce | Reduce | Reduce | Reduce | NO | 15.14 ± 2.16 | |
Cisplatin + oe-KLF2 + oe-WEE1 | Day 0 ~ 6 | Bright and clean | Normal | Normal | Normal | Normal | NO | 20.82 ± 1.65 |
Day 9 | Bright and clean | Normal | Normal | Normal | Normal | NO | 20.95 ± 2.08 | |
Day 12 | Bright and clean | Normal | Normal | Normal | Normal | NO | 20.63 ± 2.29 | |
Day 15 | Bright and clean | Normal | Normal | Normal | Normal | NO | 19.92 ± 2.41 | |
Day 18 | Dull and messy | Reduce | Reduce | Reduce | Reduce | NO | 19.18 ± 2.32 | |
Day 21 | Dull and messy | Reduce | Reduce | Reduce | Reduce | NO | 18.59 ± 1.94 | |
Day 24 | Dull and messy | Reduce | Reduce | Reduce | Reduce | NO | 17.84 ± 2.28 |