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C/EBPβ binding to the promoter region of HOTAIR during differentiation. (A) Cycloheximide (CHX) significantly impaired the up-regulated expression of HOTAIR by ATRA. (B) C/EBPβ was upregulated after ATRA-treatment. (C) Schematic representation of predicted C/EBPβ binding sites around the promoter region of HOTAIR. (D) The predicted binding site of C/EBPβ in HOTAIR promoter (−1747 and −925) was significantly increased after ATRA treatment
