Figure 3.

Indicators of expression for the genes with a high coefficient of variation (CV) in healthy human heart left ventricle tissue. (A) protein abundance [21], (B) mRNA abundance [21], (C) protein-to-mRNA ratios [21], (D) translation efficiency (TE) [16], (E) protein half-lives [23], and (F) mRNA half-lives [22] for genes with a high coefficient of variation of the genome. As a positive control, we used the top 5% most abundant proteins of cardiac proteome [21]. ANOVA Kruskal-Wallis test *0.011, **0.0054, and ****<0.0001