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. Author manuscript; available in PMC: 2021 Oct 4.
Published in final edited form as: Surgery. 2020 Jun 4;168(2):244–252. doi: 10.1016/j.surg.2020.04.013

Table II.

Number and % of total number of patients who filled initial postoperative prescription by LIS status

All (N = 18,433) No LIS (n = 16,544) LIS (full subsidy, n = 1,551) LIS (partial subsidy, n = 338) P value



No. % No. % No. %
Preoperative opioid use < .001
 Naïve 7,726 7,305 44.2% 325 21.0% 96 28.4%
 Intermittent 7,159 6,524 39.4% 515 33.2% 120 35.5%
 Chronic 3,548 2,715 16.4% 711 45.8% 122 36.1%
Surgery < .001
 Hip arthroplasty 4,169 3,837 23.2% 266 17.2% 66 19.5%
 Knee arthroplasty 9,240 8,333 50.4% 753 48.5% 154 45.6%
 Spine arthroplasty or fusion 3,263 2,852 17.2% 344 22.2% 67 19.8%
 Shoulder arthroplasty 1,761 1,522 9.2% 188 12.1% 51 15.1%
Age < .001
 65–69 6,026 5,218 31.5% 690 44.5% 118 34.9%
 70–74 6,118 5,570 33.7% 453 29.2% 95 28.1%
 75–79 3,946 3,610 21.8% 267 17.2% 69 20.4%
 80–84 1,774 1,627 9.8% 112 7.2% 35 10.4%
 85+ 569 519 3.1% 29 1.9% 21 6.2%
Sex < .001
 Male 7,089 6,673 40.3% 340 21.9% 76 22.5%
 Female 11,344 9,871 59.7% 1,211 78.1% 262 77.5%
Race < .001
 White 16,915 15,484 93.6% 1149 74.1% 282 83.4%
 Black 854 589 3.6% 227 14.6% 38 11.2%
 Others 487 313 1.9% 158 10.2% 16 4.7%
 Unknown 177 * * * * * *
Charlson comorbidity index < .001
 0 8,697 8,053 48.7% 8,053 33.8% 120 35.5%
 1–2 7,046 6,245 37.7% 6,245 42.7% 139 41.1%
 3–4 1,928 1,648 10.0% 1,648 14.9% 49 14.5%
 5+ 762 598 3.6% 598 8.6% 30 8.9%
Tobacco use 2,856 2,371 14.3% 422 27.2% 63 18.6% < .001
Mental health disorder
 Adjustment disorder 79 * * * * * *
 Anxiety 1,217 987 6.0% 190 12.3% 40 11.8% < .001
 Disruptive disorder 24 * * * * * *
 Depression 1,511 1,187 7.2% 265 17.1% 59 17.5% < .001
 Personality disorder 16 * * * * * *
 Suicide, self-harm 18 * * * * * *
 Psychosis 60 * * * * * *
 Other mental disorder 109 * * * * * *
 Alcohol, substance disorder 154 * * * * * *
Pain disorder
 Arthritis pain 15,267 13,651 82.5% 1,330 85.8% 286 84.6% .004
 Back pain 5,556 4,877 29.5% 571 36.8% 108 32.0% < .001
 Neck pain 1,921 1,614 9.8% 257 16.6% 50 14.8% < .001
 Other pain 2,763 2,327 14.1% 372 24.0% 64 18.9% < .001
*

The CMS cell size suppression policy sets minimum thresholds, 11 cases, for the display of CMS data. At least 1 of the 3 categories (ie, no LIS, LIS–full subsidy, LIS–partial subsidy) had cell size less than 11 cases.